Smad3 Monoclonal Antibody - BT-MCA1131

Smad3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1131-50, BT-MCA1131-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Research Areas: Signal transduction; Epigenetics and nuclear signaling; Cancer; Stem cells; Metabolism

Target Protein: SMAD3

Applications: WB, IF, ICC, ELISA

Reactivity: Human,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Mothers against decapentaplegic homolog 3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P84022; Mouse: Q8BUN5

Synonyms: SMAD3; MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3

GeneID: Human: 4088; Mouse: 17127

Research Use Only