SMAD4 Monoclonal Antibody - BT-MCA2271

SMAD4 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2271-50, BT-MCA2271-100

Citations, Manuals and MSDS Available upon request.

Background: Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily; SMAD4 is the common SMAD (co-SMAD). Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. May act as a tumor suppressor. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome.

Research Areas: Signal Transduction

Target Protein: SMAD4

Applications: WB, IHC, ICC, FCM

Reactivity: Human, Mouse

Clonality: Monoclonal

Clone ID: 4G1C6

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: SMAD4

Immunogen: Purified recombinant fragment of human SMAD4 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 65kDa

UniProt Accession: Q13485

Synonyms: JIP, DPC4, MADH4, SMAD4

GeneID: 4089

Research Use Only