Smad6 Monoclonal Antibody - BT-MCA1139

Smad6 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1139-50, BT-MCA1139-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.

Research Areas: Signal transduction; Epigenetics and nuclear signaling; Stem cells; Microbiology; Cardiovascular

Target Protein: SMAD6

Applications: WB, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Mothers against decapentaplegic homolog 6

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O43541; Mouse: O35182

Synonyms: SMAD6; MADH6; Mothers against decapentaplegic homolog 6; MAD homolog 6; Mothers against DPP homolog 6; SMAD family member 6; SMAD 6; Smad6; hSMAD6

GeneID: Human: 4091

Research Use Only