Product Description

SMAD7 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21252-50, RA21252-100

Citations, Manuals and MSDS Available upon request.

Background: SMAD family member 7 (SMAD7) Homo sapiens The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3) . Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 4092

Protein MW (KDa): 46

SWISS: O15105

Source: Rabbit

Research Use Only