sMtCK Monoclonal Antibody - BT-MCA1146

sMtCK Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1146-50, BT-MCA1146-100

Citations, Manuals and MSDS Available upon request.

Background: Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gen

Research Areas: Tags and; cell markers; Signal Transduction; Metabolism

Target Protein: CKMT2

Applications: WB

Reactivity: Human,Mouse,Rat,Dog,Pig,Rabbit

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Creatine kinase S-type mitochondrial

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P17540; Mouse: Q6P8J7; Rat: P09605

Synonyms: CKMT2; Creatine kinase S-type; mitochondrial; Basic-type mitochondrial creatine kinase; Mib-CK; Sarcomeric mitochondrial creatine kinase; S-MtCK

GeneID: Human: 1160; Mouse: 76722

Research Use Only