Product Description

SMYD2 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB0147-50, MB0147-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: SMYD2 (SET and MYND domain containing 2), also known as KMT3C, HSKM-B or ZMYND14, is a 433 amino acid protein that contains one SET domain and one MYND-type zinc finger. Expressed at high levels in liver, heart, kidney, ovary and brain, SMYD2 functions as a lysine methyltransferase that, via methylation of p53, may play a role in repressing p53-mediated transcriptional regμlation. The gene encoding MSYD2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3, 000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: FC

Alternate Names: HSKM-B, Histone methyltransferase SMYD2, EC=2.1.1.43, Lysine N-methyltransferase 3C, SET and MYND domain-containing protein 2, KMT3C, HSKM-B, ZMYND14

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Recombinant fμll length Human SMYD2.

Dilution: FC 1:50 - 1:100

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: SMYD2 monoclonal antibody detects endogenous levels of SMYD2 protein.

Molecular Weight: ~ 50 kDa

Pathway: Epigenetic Writers and Erasers of Histone H3,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NRG4

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only