SNAI2 Monoclonal Antibody - BT-MCA4755

SNAI2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4755-50, BT-MCA4755-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity.The tumor suppressor protein p53 induces Slug expression in gamma-irradiated cells; Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Research Areas: Neuroscience, Cancer, Stem cells, Epigenetics and nuclear signaling, Developmental biology

Target Protein: SNAI2

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2H5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: SNAI2

Immunogen: Purified recombinant fragment of human SNAI2 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 30kDa

UniProt Accession: O43623

Synonyms: SLUG, WS2D, SLUGH1, MGC10182, SNAI2

GeneID: 6591

Research Use Only