Product Description

SNRPD3 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11619-50, MB11619-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P62318

Host: Rabbit

Reactivity: Human, Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346). Is also a component of the minor U12 spliceosome (PubMed:15146077). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing .

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SNRPD3 in C6, HelaLysates using SNRPD3 antibody.

Bioworld Molecular Weight: Calculated MW: 14 kDa; Observed MW: 14 kDa

Specificity: IgG

Alternative Name: SMD3; Sm-D3

Immunogen: A synthetic peptide of human SNRPD3

Conjugate: Unconjugated

Modification: Unmodified