Product Description

SNUT1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34928-50, RA34928-100

Citations, Manuals and MSDS Available upon request.

Background: squamous cell carcinoma antigen recognized by T-cells 1 (SART1) Homo sapiens This gene encodes two proteins, the SART1 (800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1 (259) protein expressed in the cytosol of epithelial cancers. The SART1 (259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1 (259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1 (259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1 (259) protein is found to be essential for the recruitment of the tri-snR

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 9092

Protein MW (KDa): 88

SWISS: O43290

Source: Rabbit

Research Use Only