SOD-1 Monoclonal Antibody - BT-MCA1149

SOD-1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1149-50, BT-MCA1149-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Research Areas: Signal transduction; Cancer; Cell biology; Metabolism

Target Protein: SOD1

Applications: WB, IF, ICC, FCM, ELISA

Reactivity: Human,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Superoxide dismutase (Cu-Zn)

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P00441; Mouse: P08228

Synonyms: SOD1; Superoxide dismutase (Cu-Zn); Superoxide dismutase 1; hSod1

GeneID: Human: 6647; Mouse: 20655

Research Use Only