SOX-2 Monoclonal Antibody - BT-MCA1153

SOX-2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1153-50, BT-MCA1153-100

Citations, Manuals and MSDS Available upon request.

Background: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Research Areas: Epigenetics and nuclear signaling; Neuroscience; Developmental biology; Stem cells

Target Protein: SOX2

Applications: WB, IHC-p, IF, ICC, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Transcription factor SOX-2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P48431; Mouse: P48432

Synonyms: SOX2; Transcription factor SOX-2

GeneID: Human: 6657

Research Use Only