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SOX2 Polyclonal Antibody - E-AB-93387

SOX2 Polyclonal Antibody - E-AB-93387

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SOX2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-93387-60, E-AB-93387-120, E-AB-93387-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: SOX2

Target Synonym: ANOP3; MCOPS3; SOX2; SRY-box 2

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Neuroscience, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P48431

Background: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human SOX2

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Calculated MW: 34kDa

Observed MW: 36kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only

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