SPARC Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14494-20, A14494-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 35kDa
Observed Molecular Weight: 35kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 6678
SWISS: P09486
Alternate Names: ON; ONT; OI17; BM-40; SPARC
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:100 IF/ICC, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Kinase, Tyrosine kinases, Cell Biology Developmental Biology, Cell Cycle, Cell cycle inhibitors, Cytoskeleton, Extracellular Matrix, Bone, Stem Cells, Mesenchymal Stem Cells, Cardiovascular, Angiogenesis.
NCBI Alias: SPARC
Research Use Only