Product Description

SPHK1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34996-50, RA34996-100

Citations, Manuals and MSDS Available upon request.

Background: sphingosine kinase 1 (SPHK1) Homo sapiens The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 8877

Protein MW (KDa): 42

SWISS: Q9NYA1

Source: Rabbit

Research Use Only