Product Description

SphK2 (phospho Thr614) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29991-50, RA29991-100

Citations, Manuals and MSDS Available upon request.

Background: sphingosine kinase 2 (SPHK2) Homo sapiens This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Alternative Names: SPHK2; Sphingosine kinase 2; SK 2; SPK 2

Applications: IHC-p; IF (paraffin section) ; WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 56848

SWISS: Q9NRA0

Source: Rabbit

Research Use Only