Product Description

SPY2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35023-50, RA35023-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: sprouty RTK signaling antagonist 2 (SPRY2) Homo sapiens This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 34

Protein Molecular Weight (kDa): 34

Storage: -20°C/1 year

Human Gene ID: 10253

Human SwissProt Number: O43597

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only