Product Description

SRXN1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65423-50, BS65423-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Sμlfiredoxin, also designated Sμlfiredoxin-1 and chromosome 20 open reading frame 139 (C20orf139), is a cytoplasmic antioxidant protein involved in signaling through catalytic reduction of oxidative modifications. It regμlates peroxiredoxins (PRXs), a family of proteins that reduce hydroperoxides, by reducing the conserved cysteine from sμlfinic to sμlfenic acid. This impacts the role of PRX in the reduction of other downstream transcription factors and kinase signaling pathways. The Sμlfiredoxin protein specifically acts on the PRDX1, PRDX2, PRDX3 and PRDX4 peroxiredoxins, but not on PRDX5 or PRDX6. Sμlfiredoxin acts as a phosphotransferase and an athioltransferase and is widely expressed, with highest levels detected in lung, spleen, kidney and thymus tissues.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit

Host: Rabbit

Applications: WB

Alternate Names: C20orf1392, Chromosome 20 open reading frame 139, dJ850E9.2, Npn3, Npn31, SRX1, SRXN 1, Sμlfiredoxin 1, Sμlfiredoxin 1 homolog (S. cerevisiae), Sμlfiredoxin 1 homolog, YKL086W, SRXN1_HUMAN.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human SRXN1:45-137/137

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: SRXN1 Polyclonal Antibody detects endogenous levels of SRXN1 protein.

Molecular Weight: 15 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9BYN0

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only