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STAB2 Polyclonal Antibody-BS70708
STAB2 Polyclonal Antibody-BS70708
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$342.59 CAD
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$342.59 CAD
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STAB2 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS70708-50, BS70708-100
Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Swiss-Prot: Q8WWQ8
Host: Rabbit
Reactivity: Mouse
Applications: ELISA IHC ICC IF
All Applications: ELISA 1:5000-10000
IHC 1:100-500
ICC 1:100-500
IF 1:100-500
Background: This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.
Purification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: STAB2 polyclonal antibody detects endogenous levels of STAB2 protein.
Bioworld Molecular Weight: ~ 154, 275 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Tissue/cell: mouse spleen tissue;4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0), Boiling bathing for 15min;Blocking buffer at 37℃ for 20 min;
Incubation: Anti-Stabilin 2 Polyclonal Antibody, Unconjugated 1:200, overnight at 4°C; TheSecondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. DAPI was used to stain the cell nuclei.
Alternative Name: STAB 2; 190 kDa form stabilin-2; 190 kDa hyaluronan receptor for endocytosis; EGF-like; FAS1 EGF-like and X-link domain-containing adhesion molecule 2; Fasciclin; FEEL-2; FEEL2; FELL; FEX2; HARE; Hyaluronan receptor for endocytosis; laminin-type EGF-like and link domain-containing scavenger receptor 2; link domain-containing scavenger receptor 2; STAB-2; Stab2; STAB2_HUMAN.
Immunogen: KLH conjugated synthetic peptide derived from human Stabilin 2 :2201-2300/2551
Conjugate: Unconjugated
Modification: Unmodified
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