Stat4 Polyclonal Antibody - BT-AP14541

Stat4 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14541-20, BT-AP14541-50, BT-AP14541-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

Research Areas: Epigenetics and nuclear signaling; Cancer; Signal transduction

Target Protein: STAT4

Applications: WB, IHC-p, IF

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Signal transducer and activator of transcription 4

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q14765; Mouse: P42228

Synonyms: Signal transducer and activator of transcription 4; STAT4; Signal transducer and activator of transcription 4

GeneID: Human: 6775

Research Use Only