Product Description

Stat5 (phospho-S726/731) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS4464-50, BS4464-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Stat 5a protein is a transcription factor activated by hormone and cytokines. Two highly related, but distinct Stat 5 genes (Stat 5a and Stat 5b) were identified in mouse. The amino acid sequences of Stat 5a and Stat 5b show 96% sequence similarity, and both proteins are co expressed in most tissues of both virgin and lactating mice. However, differential accumμlation of Stat 5a and Stat 5b mRNA has been reported for both muscle and mammary tissue. Stat 5a is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Signal transducer and activator of transcription 5A, STAT5A, STAT5, Signal transducer and activator of transcription 5B, STAT5B

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: Synthetic peptide derived from human stat5a around the phosphorylation site of S726.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Stat5 (phospho-S726/731) polyclonal antibody detects endogenous levels of Stat5a protein only when phosphorylated at Ser726 and/or Stat5b protein only when phosphorylated at Ser731.

Molecular Weight: ~ 90 kDa

Pathway: Immune Cell Signaling, Jak Stat: IL-6 Receptor Signaling, T cell receptor signaling,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P42229/P51692

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only