STK11 Monoclonal Antibody - BT-MCA4776

STK11 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4776-50, BT-MCA4776-100

Citations, Manuals and MSDS Available upon request.

Background: Essential role in G1 cell cycle arrest. Phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Tumor suppressor.serine/threonine kinase 11,with two alternatively spliced isoforms,expressed in all tissues,strongly homolog of Xenopus early embryonic kinase 1 (XEEK1),tumor suppressor gene in hamartomas syndrome and in left sided colon carcinogenesis,mutated in sporadic testicular cancer,malignant melanomas and laryngeal tumors,playing a minor role in the development of ovarian carcinoma.LKB1 is a potential target for atherosclerosis and cancer and is shown to be mutated in patients with Peutz-Jeghers cancer syndrome. Tissue specificity: Ubiquitously expressed. Strongest expression in testis and fetal liver.

Research Areas: Cell Biology

Target Protein: STK11

Applications: WB, FCM

Reactivity: Human, Mouse, Monkey

Clonality: Monoclonal

Clone ID: 4H12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: STK11

Immunogen: Purified recombinant fragment of human STK11 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 54kDa

UniProt Accession: Q15831

Synonyms: PJS, LKB1, STK11

GeneID: 6794

Research Use Only