STK3 Polyclonal Antibody - BT-AP14566

STK3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14566-20, BT-AP14566-50, BT-AP14566-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Signal transduction; Cell biology

Target Protein: STK3

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Serine/threonine-protein kinase 3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q13188; Mouse: Q9JI10; Rat: O54748

Synonyms: Serine/threonine-protein kinase 3;EC 2.7.11.1;Mammalian STE20-like protein kinase 2;MST-2;STE20-like kinase MST2;Serine/threonine-protein kinase Krs-1 [Cleaved into: Serine/threonine-protein

GeneID: Human: 6788

Research Use Only