SURF-1 Polyclonal Antibody - BT-AP08683

SURF-1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP08683-20, BT-AP08683-50, BT-AP08683-100

Citations, Manuals and MSDS Available upon request.

Background: SURF1 encodes surfeit locus protein 1 localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. Surfeit locus protein 1 is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.

Research Areas: Tags and Cell Markers

Target Protein: SURF1

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: SURF-1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 33331

UniProt Accession: Human: Q15526; Mouse: P09925; Rat: Q9QXU2

Synonyms: SURF1; SURF-1; Surfeit locus protein 1

GeneID: Human: 6834; Mouse: 20930; Rat: 64463

Research Use Only