Survivin Monoclonal Antibody - BT-MCA4614

Survivin Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4614-50, BT-MCA4614-100

Citations, Manuals and MSDS Available upon request.

Background: Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.

Research Areas: Others

Target Protein: Survivin

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2H5H2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: Survivin

Immunogen: Purified recombinant fragment of Survivin expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: O15392

Synonyms: API4, EPR-1, BIRC5

GeneID: 332

Research Use Only