TAB2 Monoclonal Antibody - BT-MCA3729

TAB2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3729-50, BT-MCA3729-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.

Research Areas: Signal transduction, Immunology

Target Protein: TAB2

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3B5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: TAB2

Immunogen: Purified recombinant fragment of human TAB2 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 80kDa

UniProt Accession: Q9NYJ8

Synonyms: CHTD2, FLJ21885, KIAA0733, MAP3K7IP2, TAB2

GeneID: 23118

Research Use Only