TAF II p18 Polyclonal Antibody - BT-AP08793

TAF II p18 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP08793-20, BT-AP08793-50, BT-AP08793-100

Citations, Manuals and MSDS Available upon request.

Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF13 (TATA-box binding protein associated factor 13) encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: TAF13

Applications: IHC-p, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: TAF II p18 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 14287

UniProt Accession: Human: Q15543; Mouse: P61216

Synonyms: TAF13; TAF2K; TAFII18; Transcription initiation factor TFIID subunit 13; Transcription initiation factor TFIID 18 kDa subunit; TAF(II)18; TAFII-18; TAFII18

GeneID: Human: 6884; Mouse: 99730

Research Use Only