Product Description

TAF II p250 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30270-50, RA30270-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: TATA-box binding protein associated factor 1 (TAF1) Homo sapiens Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also bin

Reactivity: Human, Mouse

Host: Rabbit

Applications: IHC-p, IF (paraffin section), ELISA

Alternate Names: TAF1, BA2R, CCG1, CCGS, TAF2A, Transcription initiation factor TFIID subunit 1, Cell cycle gene 1 protein, TBP-associated factor 250 kDa, p250, Transcription initiation factor TFIID 250 kDa subunit, TAF (II)250, TAFII-250, TAFII250

Clonality: Polyclonal

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Storage: -20°C/1 year

Human Gene ID: 6872

Human SwissProt Number: P21675

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only