Tau (Acetyl Lys686) Polyclonal Antibody - BT-AP14755

Tau (Acetyl Lys686) Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14755-20, BT-AP14755-50, BT-AP14755-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimerandapos;s disease, Pickandapos;s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Research Areas: Neuroscience; Signal transduction

Target Protein: MAPT

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Microtubule-associated protein tau

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P10636; Mouse: P10637; Rat: P19332

Synonyms: Microtubule-associated protein tau; MAPT; MAPTL; MTBT1; TAU; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau

GeneID: Human: 4137; Mouse: 17762

Research Use Only