TBK1 Polyclonal Antibody - BT-AP08858

TBK1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP08858-20, BT-AP08858-50, BT-AP08858-100

Citations, Manuals and MSDS Available upon request.

Background: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The TANK binding kinase 1 encoded by TBK1 is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.

Research Areas: Signal Transduction

Target Protein: TBK1

Applications: IHC-p, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: TBK1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 83642

UniProt Accession: Human: Q9UHD2; Mouse: Q9WUN2

Synonyms: TBK1; NAK; Serine/threonine-protein kinase TBK1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1

GeneID: Human: 29110; Mouse: 56480

Research Use Only