TBL1X Monoclonal Antibody - BT-MCA1186

TBL1X Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1186-50, BT-MCA1186-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have bee

Research Areas: Epigenetics and nuclear signaling; Cancer; Metabolism

Target Protein: TBL1X

Applications: WB, ELISA

Reactivity: Human,Monkey

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: F-box-like,WD repeat-containing protein TBL1X

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O60907; Mouse: Q9QXE7

Synonyms: TBL1X; TBL1; F-box-like; WD repeat-containing protein TBL1X; SMAP55; Transducin beta-like protein 1X; Transducin-beta-like protein 1; X-linked

GeneID: Human: 6907

Research Use Only