TBX21 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A4682-20, A4682-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG) . Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 58kDa
Observed Molecular Weight: 58kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 30009
SWISS: Q9UL17
Alternate Names: TBET; IMD88; T-PET; T-bet; TBLYM; TBX21
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Immunology Inflammation, Stem Cells, Hematopoietic Progenitors.
NCBI Alias: TBX21
Research Use Only