TBX5 Monoclonal Antibody - BT-MCA1192

TBX5 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1192-50, BT-MCA1192-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

Research Areas: Epigenetics and nuclear signaling; Cardiovascular

Target Protein: TBX5

Applications: WB, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: T-box transcription factor TBX5

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q99593; Mouse: P70326

Synonyms: TBX5; T-box transcription factor TBX5; T-box protein 5

GeneID: Human: 6910

Research Use Only