TBX5 Monoclonal Antibody - BT-MCA3066

TBX5 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3066-50, BT-MCA3066-100

Citations, Manuals and MSDS Available upon request.

Background: TBX5, also known as T-box 5. It is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The TBX5 protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

Research Areas: Epigenetics and nuclear signaling, Cardiovascular

Target Protein: TBX5

Applications: WB

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7B11

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: TBX5

Immunogen: Purified recombinant fragment of TBX5 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 53kDa

UniProt Accession: Q99593

Synonyms: HOS, TBX5

GeneID: 6910

Research Use Only