Product Description

TCAP Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18784-60, E-AB-18784-120, E-AB-18784-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TCAP

Target Synonym: 19 kDa sarcomeric protein ; CMD1N; CMH25; LGMD2G; Limb girdle muscular dystrophy 2G (autosomal recessive) ; T-cap; Tcap; TELE; Telethonin; TELT; Titin cap protein; Titin-cap

Research Areas: Cancer, Cardiovascular

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O15273

Background: Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.

Concentration: 1.02 mg/mL

Immunogen: Fusion protein of human TCAP

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only