TCP-1 Epsilon Polyclonal Antibody - BT-AP08899

TCP-1 Epsilon Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP08899-20, BT-AP08899-50, BT-AP08899-100

Citations, Manuals and MSDS Available upon request.

Background: The chaperonin containing TCP1 subunit 5 encoded by CCT5 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13.

Research Areas: Signal Transduction

Target Protein: CCT5

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: TCP-1 epsilon Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 59671

UniProt Accession: Human: P48643; Mouse: P80316; Rat: Q68FQ0

Synonyms: CCT5; CCTE; KIAA0098; T-complex protein 1 subunit epsilon; TCP-1-epsilon; CCT-epsilon

GeneID: Human: 22948; Mouse: 12465; Rat: 294864

Research Use Only