TEK Polyclonal Antibody - E-AB-63261

TEK Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-63261-60, E-AB-63261-120, E-AB-63261-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TEK

Target Synonym: TEK; CD202B; GLC3E; TIE-2; TIE2; VMCM; VMCM1; Tie2

Research Areas: Cancer,Cardiovascular,Developmental Biology,Signal Transduction,Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q02763

Background: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human TEK

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:1000

Calculated MW: 109kDa/121kDa/125kDa

Observed MW: 150KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only