TFAM Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A13552-20, A13552-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA, ChIP
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 29kDa
Observed Molecular Weight: 25kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 7019
SWISS: Q00059
Alternate Names: TCF6; MTTF1; MTTFA; TCF6L1; TCF6L2; TCF6L3; MTDPS15; TFAM
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. ChIP, 5μg antibody for 10μg-15μg of Chromatin
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, RNA Binding, Cancer, Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Wnt -Catenin Signaling Pathway, Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers, Nucleotide metabolism, Neuroscience, Neurodegenerative Diseases, Cardiovascular, Heart, Cardiogenesis.
NCBI Alias: TFAM
Research Use Only