TFIIH p89 Monoclonal Antibody - BT-MCA1199

TFIIH p89 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1199-50, BT-MCA1199-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: ERCC3

Applications: WB

Reactivity: Human,Mouse,Rat,Bovine,Dog

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: TFIIH basal transcription factor complex helicase XPB subunit

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P19447; Mouse: P49135; Rat: Q4G005

Synonyms: ERCC3; XPB; XPBC; TFIIH basal transcription factor complex helicase XPB subunit; Basic transcription factor 2 89 kDa subunit; BTF2 p89; DNA excision repair protein ERCC-3; DNA repair protein complementing XP-B cells; TFIIH basal transcripti

GeneID: Human: 2071; Mouse: 13872; Rat: 291703

Research Use Only