Product Description

TGFBR3 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60728-50, BS60728-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: A total of three members of the TGFβ family, TGFβ1, TGFβ2 and TGFβ3, have been identified in mammals. Each is synthesized as a latent precursor that is subsequently cleaved forming the 112 amino acid growth factor which becomes active upon dimerization. TGFβs mediate their activity by high affinity binding to the type II receptor transmembrane protein with a cytoplasmic serine-threonine kinase domain. TGFβ RIII (transforming growth factor beta receptor type 3), also known as TGFBR3 or TGFR-3, is an 850 amino acid secreted and single-pass type I membrane protein that contains one ZP domain and may assist in capturing TGFβ for presentation to signaling receptors.TGFβ RIII undergoes post-translational modification by glycosaminoglycan groups (GAG) and is encoded by a gene that maps to human chromosome 1p22.1.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Transforming growth factor beta receptor type 3, TGF-beta receptor type 3, TGFR-3, Betaglycan, Transforming growth factor beta receptor III, TGF-beta receptor type III, TGFBR3

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human TGFBR3

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TGFBR3 polyclonal antibody detects endogenous levels of TGFBR3 protein.

Molecular Weight: ~ 93 kDa

Pathway: Cell Cycle Control G1 S Checkpoint, TGFβ Smad signaling ,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q03167

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only