TIA1 Monoclonal Antibody - BT-MCA4663

TIA1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4663-50, BT-MCA4663-100

Citations, Manuals and MSDS Available upon request.

Background: The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene.

Research Areas: Epigenetics and nuclear signaling, Cancer, Cell biology, Immunology

Target Protein: TIA1

Applications: FCM

Clonality: Monoclonal

Clone ID: 2A10B12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: TIA1

Immunogen: Purified recombinant fragment of human TIA1 (AA: 1-215) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 43kDa

UniProt Accession: P31483

Synonyms: WDM, TIA-1

GeneID: 7072

Research Use Only