Product Description

TIGAR Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35318-50, RA35318-100

Citations, Manuals and MSDS Available upon request.

Background: TP53 induced glycolysis regulatory phosphatase (TIGAR) Homo sapiens This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 57103

Protein MW (KDa): 29

SWISS: Q9NQ88

Source: Rabbit

Research Use Only