TIN2 Polyclonal Antibody - BT-AP09039

TIN2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09039-20, BT-AP09039-50, BT-AP09039-100

Citations, Manuals and MSDS Available upon request.

Background: TINF2 encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The TERF1 interacting nuclear factor 2 encoded by TINF2 is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: TINF2

Applications: WB, IHC-p, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: TIN2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 50023

UniProt Accession: Human: Q9BSI4; Mouse: Q9QXG9

Synonyms: TINF2; TIN2; TERF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2

GeneID: Human: 26277

Research Use Only