Product Description

TKN1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES11351-50, ES11351-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human protein. at AA range: 20-100

Isotype: IgG

Target: TKN1

Specificity: TKN1 Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Adrenal medulla, Blood, Brain, Small intestine, Testis,

Observed Band (KD): 14kD

Fields: Neuroactive ligand-receptor interaction

Function: Function: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles
Online Information: Neurokinin-1 entry,Similarity: Belongs to the tachykinin family

Subcellular Location: Secreted

Storage and Stability: -20°C/1 year

Gene Name: TAC1 NKA NKNA TAC2

Protein Name: Protachykinin-1 (PPT) [Cleaved into: Substance P, Neurokinin A (NKA) (Neuromedin L) (Substance K), Neuropeptide K (NPK), Neuropeptide gamma, C-terminal-flanking peptide]

Mouse SwissProt Number: P41539

Rat SwissProt Number: P06767

Research Use Only