TLK1 Polyclonal Antibody - BT-AP09055

TLK1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09055-20, BT-AP09055-50, BT-AP09055-100

Citations, Manuals and MSDS Available upon request.

Background: Serine/threonine-protein kinase tousled-like 1 encoded by TLK1 is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: TLK1

Applications: WB, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: TLK1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 86700

UniProt Accession: Human: Q9UKI8; Mouse: Q8C0V0

Synonyms: TLK1; KIAA0137; Serine/threonine-protein kinase tousled-like 1; PKU-beta; Tousled-like kinase 1

GeneID: Human: 9874

Research Use Only