TLR2 Monoclonal Antibody - BT-MCA3437

TLR2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3437-50, BT-MCA3437-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Research Areas: Signal transduction, Immunology, Microbiology, Cardiovascular

Target Protein: TLR2

Applications: WB

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2D6

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: TLR2

Immunogen: Purified recombinant fragment of human TLR2 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 100kDa

UniProt Accession: O60603

Synonyms: TIL4, CD282, TLR2

GeneID: 7097

Research Use Only