Product Description

TM7SF2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16924-60, E-AB-16924-120, E-AB-16924-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TM7SF2

Target Synonym: ANG1; NET47; DHCR14A

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O76062

Background: Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4, 4-dimethyl-5-alpha-cholesta-8, 14, 24-trien-3-beta-ol to 4, 4-dimethyl-5-alpha-cholesta-8, 24-dien-3-beta-ol and NADP+.

Concentration: 0.6 mg/mL

Immunogen: Synthetic peptide of human TM7SF2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Calculated MW: 46kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only