TMEM185A Polyclonal Antibody - BT-AP09083

TMEM185A Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09083-20, BT-AP09083-50, BT-AP09083-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by TMEM185A (transmembrane protein 185A) is predicted to be a transmembrane protein. TMEM185A is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of TMEM185A has been defined on the X chromosome.

Research Areas: Cell Biology

Target Protein: TMEM185A

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: TMEM185A Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 40647

UniProt Accession: Human: Q8NFB2

Synonyms: TMEM185A; CXorf13; FAM11A; Transmembrane protein 185A; Protein FAM11A

GeneID: Human: 84548

Research Use Only