TNFRSF11A Monoclonal Antibody - BT-MCA3210

TNFRSF11A Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3210-50, BT-MCA3210-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

Research Areas: Signal transduction, Cardiovascular, Immunology

Target Protein: TNFRSF11A

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 8H8B2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: TNFRSF11A

Immunogen: Purified recombinant fragment of human TNFRSF11A (AA: extra 30-212) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 66kDa

UniProt Accession: Q9Y6Q6

Synonyms: FEO, OFE, ODFR, OSTS, PDB2, RANK, CD265, OPTB7, TRANCER, LOH18CR1

GeneID: 8792

Research Use Only