TNFRSF25 Monoclonal Antibody - BT-MCA3855

TNFRSF25 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3855-50, BT-MCA3855-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008]

Research Areas: Cell Biology

Target Protein: TNFRSF25

Applications: IHC, FCM

Clonality: Monoclonal

Clone ID: 4G12H11

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: TNFRSF25

Immunogen: Purified recombinant fragment of human TNFRSF25 (AA: extra(25-199)) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 45.4kDa

UniProt Accession: Q93038

Synonyms: DR3, TR3, DDR3, LARD, APO-3, TRAMP, WSL-1, GEF720, WSL-LR, PLEKHG5, TNFRSF12

GeneID: 8718

Research Use Only