TOP1MT Polyclonal Antibody - E-AB-65363

TOP1MT Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-65363-60, E-AB-65363-120, E-AB-65363-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TOP1MT

Target Synonym: TOP1MT

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q969P6

Background: This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human TOP1MT (NP_443195.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:200-1:2000

Calculated MW: 58kDa/69kDa

Observed MW: 70kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only